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Friday, 3/7/2026 | 08:02 GMT+7

A 78-year-old woman with lung cancer metastatic to the liver

Thanh, 78, experienced cough and shortness of breath for two weeks due to lung cancer metastatic to the liver, and doctors used a combination of two chemotherapy drugs to manage the disease.

Initial CT scan results at Tam Anh General Hospital revealed a large tumor in the right lung hilum and mediastinum, accompanied by multiple lesions in the right lung parenchyma. Master of Science, Doctor Luu Thao Ngoc, from the Oncology Department, explained that the tumor was compressing the airway, leading to Thanh’s persistent respiratory symptoms.

An abdominal ultrasound further detected liver lesions suspected of metastasis. While pleural fluid aspiration results were inconclusive for cancer confirmation, a subsequent liver biopsy, combined with histopathological and immunohistochemical tests, definitively diagnosed Thanh with extensive-stage small cell lung cancer that had metastasized to the liver.

Doctors prescribed a chemotherapy regimen combining two different drugs. Following three treatment cycles, Thanh’s symptoms improved. A follow-up CT scan, conducted to evaluate treatment efficacy, revealed significant shrinkage of the lesions in both her lungs and liver. She will continue to receive chemotherapy for three more cycles, undergoing close monitoring and regular assessments of her treatment response. This ongoing evaluation will help doctors formulate an appropriate treatment strategy for the subsequent stages of her care.

Thanh underwent a CT scan to assess results after three treatment cycles. *Photo: Tam Anh General Hospital*

Doctor Ngoc explained that small cell lung cancer, though accounting for only 10-15% of lung cancer cases, is aggressive. It exhibits a high proliferation rate, readily invades nearby structures, and often metastasizes early to organs such as the liver, brain, bones, or adrenal glands. A key aspect of small cell lung cancer is its responsiveness to initial chemotherapy, which helps manage symptoms, reduce tumor size, and enhance the patient's quality of life.

Lung cancer is one of the most common cancers globally and a leading cause of death. It is primarily categorized into two types: non-small cell lung cancer and small cell lung cancer.

Doctor Ngoc advises individuals not to overlook persistent respiratory symptoms such as a cough lasting more than two to three weeks, shortness of breath, wheezing, chest pain, or unexplained weight loss. Those with a long history of smoking or regular exposure to smoke, dust, and toxic chemicals should undergo regular medical check-ups and screenings as recommended by a doctor. Early detection significantly increases the chances of effective treatment, improving both the quality of life and prognosis for lung cancer patients.

Hieu Nguyen

*Patient's name has been changed

Readers can submit questions about cancer here for doctors to answer
By VnExpress: https://vnexpress.net/ba-cu-78-tuoi-ung-thu-phoi-di-can-gan-5092411.html
Tags: cancer treatment cancer metastasis lung cancer

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