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Sunday, 18/1/2026 | 17:01 GMT+7

Female physiological decline: stress or hormonal imbalance?

A 38-year-old woman from Dong Nai, Minh Anh, reports experiencing prolonged stress and vaginal dryness, impacting her marital life. She questions whether her symptoms are due to stress or a hormonal decline.

Answer:

At 38, women typically have not reached perimenopause or menopause. However, prolonged stress can directly affect the body's neuro-endocrine-genital axis. This axis, comprising the hypothalamus and pituitary gland in the brain, is closely linked to the ovaries. When stress persists, stress signals from the brain can inhibit the activity of the hypothalamus and pituitary gland, causing the ovaries to reduce estrogen secretion and vaginal lubrication. This leads to dryness, pain during intercourse, and if prolonged estrogen deficiency occurs, can hinder sexual intimacy.

Dr. Nguyen Ba My Nhi advises on hormonal decline in middle-aged women. Photo: Tam Anh General Hospital

Beyond stress, some women may experience an earlier decline in neuro-endocrine axis activity than the average age. Even before menopause, estrogen levels can decrease. In such cases, besides vaginal dryness, women may also suffer from painful and frequent urination, and urinary infections. Many require repeated antibiotic treatments without complete resolution.

It is advisable to consult an obstetrician-gynecologist to determine the specific cause and receive appropriate treatment. Timely intervention, including lifestyle adjustments, stress reduction, psychological counseling, and hormonal support when necessary, can improve this condition.

Dr. Nguyen Ba My Nhi

Specialist Doctor II, Director of Obstetrics and Gynecology Center

Tam Anh General Hospital System, TP HCM

Readers can submit questions regarding obstetrics and gynecology here for doctors to answer
By VnExpress: https://vnexpress.net/suy-giam-sinh-ly-nu-do-cang-thang-hay-roi-loan-noi-tiet-5006892.html
Tags: hormonal imbalance stress female physiology

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