According to Pharmacist Do Xuan Hoa from the Medical Information Center at Tam Anh General Hospital Ho Chi Minh City, many women seek consultations for psychological disturbances, exhibiting symptoms such as increased irritability, mood swings, and persistent fatigue. Some cases involve prolonged insomnia, poor concentration, a loss of self-confidence, easy crying, signs of depression, and diminished mood.

Many people associate perimenopause solely with irregular menstruation or hot flashes and night sweats. However, the decline in activity of the brain-pituitary-ovarian axis also causes hormonal imbalances that directly impact the brain and mental health of women.

Specifically, an imbalance in the three hormones — estrogen, progesterone, and testosterone — affects serotonin (a mood stabilizer) and dopamine (a motivator and reward chemical). These neurotransmitters are crucial for mood, sleep, and concentration. When estrogen levels fluctuate erratically, the brain becomes more sensitive to stress, making emotional regulation difficult.

Women from age 40 onward are prone to irritability and a decreased interest in things they once enjoyed. Photo: Eco Pharma

This condition impacts work, family relationships, and quality of life. Emotional disorders related to perimenopause can be treated if diagnosed early. Beyond hormonal fluctuations, feelings of sadness and a lack of self-confidence are also influenced by age-related pressures, changes in appearance, evolving childcare responsibilities, or new job demands. If not recognized promptly, prolonged insecurity can lead to depression.

Pharmacist Hoa notes that not all emotional changes are pathological. However, women should not dismiss symptoms such as prolonged sadness lasting several weeks, difficulty sleeping or sleeping excessively, and feelings of worthlessness or inadequacy. Early recognition of these signs helps women seek psychological support.

Family members should share and listen when women experience emotional disturbances. Photo: Eco Pharma

To improve psychological well-being at age 40, women need to adopt a healthy lifestyle, ensure adequate rest, get 7-8 hours of sleep each night, and increase physical activity with sports like walking, yoga, swimming, and badminton. Women should consume plenty of green vegetables and fresh fruits, while limiting sugar, salt, fats, alcohol, and stimulants. Maintaining a positive mindset and focusing on positive things by joining groups and communicating more with family and friends is also beneficial.

A healthy brain-pituitary-ovarian axis and stable hormone levels are key factors in maintaining women's health and mood. According to Pharmacist Hoa, some natural essences, such as lepidium meyenii, can enhance the activity of this axis, helping the body naturally produce the trio of hormones—estrogen, progesterone, and testosterone—in the correct and sufficient amounts according to natural needs. P.leucotomos essence helps maintain the firmness of the skin's underlying structure, supporting the prevention of skin aging and keeping skin soft and smooth.

Pharmacist Hoa states that hormone therapy or antidepressants may be considered in some cases. However, these measures carry potential risks, including an increased risk of breast cancer, high blood pressure, weight gain, and can lead to thrombotic diseases. Women should consult a gynecologist at a specialized healthcare facility for a direct examination.

Thai Thanh