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Wednesday, 17/6/2026 | 00:05 GMT+7

Why can late-night eating harm the liver?

Frequent late-night eating can lead to fat accumulation, inflammation, and impaired metabolic function, increasing the risk of fatty liver disease.

Disrupted glucose metabolism is a key concern. The liver plays a primary role in regulating blood sugar by storing, releasing, or producing glucose as needed. According to Eating Well, a habit of late-night eating can result in higher blood sugar levels because the liver processes glucose less efficiently at night. Over time, this impairs the liver's ability to regulate blood sugar, increasing the risk of non-alcoholic fatty liver disease (NAFLD).

Late-night eating can also cause inflammation. Regularly consuming high-fat and sugary foods late at night leads to fat accumulation in the liver. When this fat exceeds healthy levels, the body triggers an inflammatory response to address the damage. Prolonged inflammation can harm liver cells, reducing their ability to detoxify and metabolize nutrients. Over time, fatty liver accompanied by inflammation can progress to fibrosis, cirrhosis, and heighten the risk of many chronic liver diseases.

Eating greasy foods late at night affects liver health. Illustration: Anh Ngoc.

Eating greasy foods late at night affects liver health. Illustration: Anh Ngoc.

Disrupting the body's circadian rhythm is another consequence. The liver possesses its own circadian rhythm, which helps regulate metabolism, energy storage, and cell repair. Eating late, especially large meals close to bedtime, forces the body to continue processing nutrients when natural metabolic activities are typically winding down. This prolonged habit can disrupt metabolic circadian rhythms, impacting the liver's ability to process fats and leading to fat accumulation, according to Times of India.

To mitigate these risks, individuals should aim to finish dinner approximately two to three hours before bedtime, allowing the body sufficient time to digest food. This practice also reduces the risk of acid reflux for some people. If a late-night snack is necessary, opt for easily digestible options in moderate portions, such as yogurt, milk, nuts, or appropriate fruits, avoiding overeating to limit adverse effects on sleep and the digestive system.

For overall liver health, it is essential to combine a balanced diet, a healthy lifestyle, and regular health check-ups. Limiting saturated fats, sugary foods, alcohol, and avoiding smoking are crucial steps. Alcohol is primarily metabolized in the liver, producing acetaldehyde, a substance that can damage liver cells and promote oxidative stress. Maintaining about 150 minutes of physical activity each week helps manage weight and supports the prevention of fatty liver disease.

By Le Nguyen (Compiled)

By VnExpress: https://vnexpress.net/vi-sao-an-khuya-co-the-hai-gan-5085378.html
Tags: late-night eating liver health

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